Paired surface plasma waves biosensor using degree of coherence

Chien-Wa Ho; Sheng-Yi Chang; Nai-Chuan Chen; Ying-Feng Chang; Chien Chou

doi:10.1117/12.2001430

21 February 2013 Paired surface plasma waves biosensor using degree of coherence

Chien-Wa Ho, Sheng-Yi Chang, Nai-Chuan Chen, Ying-Feng Chang, Chien Chou

Author Affiliations +

Proceedings Volume 8597, Plasmonics in Biology and Medicine X; 85970D (2013) https://doi.org/10.1117/12.2001430
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Degree of coherence (DOC) of a paired surface plasma waves (PSPWs) in the paired surface plasma waves biosensor (PSPWB) is proposed and discussed in which a paired of surface plasma waves are excited by using a pair of highly spatial and temporal correlated P-polarized waves in a SPR device of the Kretschmann configuration. The heterodyne signal from reflected paired P-polarized laser beam is generated where the visibility of the signal is proportional to DOC of PSPWs in term of the ratio of AC and DC components of the signal. The experimental result shows that the DOC of PSPWs versus incident angle of laser beam which relates to intrinsic phonon distribution in metal film becomes much sensitive than conventional amplitude or intensity sensitive surface plasmon resonance (SPR) biosensor. Finally, the dynamic range of protein-protein interaction at ultralow concentrations is discussed.

Citation Download Citation

Chien-Wa Ho, Chien-Wa Ho, Sheng-Yi Chang, Sheng-Yi Chang, Nai-Chuan Chen, Nai-Chuan Chen, Ying-Feng Chang, Ying-Feng Chang, Chien Chou, Chien Chou, "Paired surface plasma waves biosensor using degree of coherence", Proc. SPIE 8597, Plasmonics in Biology and Medicine X, 85970D (21 February 2013); doi: 10.1117/12.2001430; https://doi.org/10.1117/12.2001430

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