21 February 2013 Plasmon saturation induced super-resolution imaging
Author Affiliations +
Proceedings Volume 8597, Plasmonics in Biology and Medicine X; 85970P (2013) https://doi.org/10.1117/12.2003815
Event: SPIE BiOS, 2013, San Francisco, California, United States
Conventionally, super-resolution imaging is achieved by manipulating the on/off switching of fluorophores, or by saturation of fluorescence emission. To prevent the photobleaching of fluorophores, we demonstrate novel superresolution imaging based on saturation of scattering from plasmonic particles, for the first time. With spectral studies, we have confirmed the saturation is directly linked to surface plasmon resonance effect. With the aid of saturation excitation microscopy, plus field concentration due to nonlinear plasmon resonance, we have achieved optical resolution below 80-nm based on scattering. Our study will open up a completely new paradigm for super-resolution microscopy.
© (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Hsuan Lee, Hsuan Lee, Tung-Yu Su, Tung-Yu Su, Yasuo Yonemaru, Yasuo Yonemaru, Ming-Ying Lee, Ming-Ying Lee, Masahito Yamanaka, Masahito Yamanaka, Ko-Fan Huang, Ko-Fan Huang, Satoshi Kawata, Satoshi Kawata, Katsumasa Fujita, Katsumasa Fujita, Shi-Wei Chu, Shi-Wei Chu, "Plasmon saturation induced super-resolution imaging", Proc. SPIE 8597, Plasmonics in Biology and Medicine X, 85970P (21 February 2013); doi: 10.1117/12.2003815; https://doi.org/10.1117/12.2003815

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