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21 February 2013 Planar chiral metamaterials for biosensing applications
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Proceedings Volume 8597, Plasmonics in Biology and Medicine X; 85970Y (2013)
Event: SPIE BiOS, 2013, San Francisco, California, United States
There has been a considerable effort recently in the development of planar chiral metamaterials. Owing to the lack of inversion symmetry, these materials have been shown to display interesting physical properties such as negative index of refraction and giant optical activity. However, the biosensing capabilities of these chiral metamaterials have not been fully explored. Ultrasensitive detection and structural characterization of proteins adsorbed on chiral plasmonic substrates was demonstrated recently using UV-visible circular dichroism (CD) spectroscopy. Second harmonic generation microscopy is an extremely sensitive nonlinear optical probe to investigate the chirality of biomaterials. In this study, we characterize the chiral response of chiral plasmonic metamaterials using second harmonic generation microscopy and CD spectroscopy. These planar chiral metamaterials, fabricated by electron-beam lithography, consist of right-handed and left-handed gold gammadions of length 400 nm and thickness 100nm, deposited on a glass substrate and arranged in a square lattice with a periodicity of 800nm.
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Sangeeta Murugkar, Israel De Leon, Matthew Horton, Hammam Qassim, Jonathan Leach, and Robert W. Boyd "Planar chiral metamaterials for biosensing applications", Proc. SPIE 8597, Plasmonics in Biology and Medicine X, 85970Y (21 February 2013);

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