Label free optimal dynamic discrimination of biological macromolecules

S. Afonina; A. Rondi; D. Kiselev; L. Bonacina; J. P. Wolf

doi:10.1117/12.2002467

15 March 2013 Label free optimal dynamic discrimination of biological macromolecules

S. Afonina, A. Rondi, D. Kiselev, L. Bonacina, J. P. Wolf

Author Affiliations +

Proceedings Volume 8611, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XIII; 86110F (2013) https://doi.org/10.1117/12.2002467
Event: SPIE LASE, 2013, San Francisco, California, United States

Abstract

The fast development of laser techniques, in particular, the generation of ultrashort femtosecond and even attosecond pulses opens new frontiers and various experimental tools for biomedical applications. The combination of pulse shaping and optimal control is a very promising tool based on coherent manipulation of wavepackets on an ultrafast time scale. It already has successfully been applied for optimal dynamic discrimination (ODD) experiments of biomolecules like free amino acids and flavins which are indistinguishable by spectroscopic means. This approach can be extended toward to label free cellular imaging and detection of chemical or biological substances.

Citation Download Citation

S. Afonina, S. Afonina, A. Rondi, A. Rondi, D. Kiselev, D. Kiselev, L. Bonacina, L. Bonacina, J. P. Wolf, J. P. Wolf, } "Label free optimal dynamic discrimination of biological macromolecules", Proc. SPIE 8611, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XIII, 86110F (15 March 2013); doi: 10.1117/12.2002467; https://doi.org/10.1117/12.2002467

ACCESS THE FULL ARTICLE

PERSONAL SIGN IN
Full access may be available with your subscription

Email or Username Forgot your username?

Password Forgot your password?

Show

Remember Email/Username on this computer

Remember Password

No SPIE account? Create an account
or Institutional Sign In via Shibboleth

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $14.40

Non-members: $18.00 ADD TO CART

Show All Keywords

Keywords/Phrases

Search In:

Publication Years