14 February 2013 Joint reconstruction and segmentation of electron tomography data
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Scanning transmission electron tomography is often used to reveal the internal structure of material samples. In this technique, a tilt series of tomographic projections is reconstructed to obtain volumetric information. The reconstructed scene is then segmented into regions with homogeneous properties to localize and quantify various material elements. Unfortunately, physical constraints limit the extent of the projection tilt series, leading to artifacts in the reconstructed volume, which can make subsequent segmentation difficult. In this work we use a different, discrete tomography, approach wherein we directly reconstruct only a limited and discrete set of pixel amplitudes, effectively performing the reconstruction and segmentation in a joint fashion. Unlike existing methods, the approach is based on direct formulation of the problem in the discrete domain. Solution of the subsequent challenging optimization problem is achieved through the iterative use of graph-cut methods applied to a physically motivated surrogate cost function. We show reconstruction results using synthetic phantom images for limited angle scenarios and compare them to conventional reconstruction techniques.
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Ahmet Tuysuzoglu, Ahmet Tuysuzoglu, W. Clem Karl, W. Clem Karl, David Castanon, David Castanon, M. Selim Unlu, M. Selim Unlu, "Joint reconstruction and segmentation of electron tomography data", Proc. SPIE 8657, Computational Imaging XI, 86570T (14 February 2013); doi: 10.1117/12.2013232; https://doi.org/10.1117/12.2013232

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