19 February 2013 High sensitivity analysis of speckle patterns: a technological challenge for biomedical optics
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Abstract
Diffuse light in tissue can be a very interesting tool for medical diagnosis, especially if one considers the fluctuations of the speckle pattern. Of course, speckle analysis suffers from the low spatial coherence of speckle patterns, and multipixel detection is required in order to increase the signal to noise ratio. There is therefore a need of a setup with a high sensitivity, capable of outputting a signal from noise through averaging on a high number of pixels, as the signal can be lower than the photon level for one image and one frame. Furthermore, such a processing has to be done at a very high acquisition rate. “Smart-pixels” arrays can represent a major breakthrough in this field.
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J.-M. Tualle, J.-M. Tualle, K. Barjean, K. Barjean, E. Tinet, E. Tinet, D. Ettori, D. Ettori, } "High sensitivity analysis of speckle patterns: a technological challenge for biomedical optics", Proc. SPIE 8659, Sensors, Cameras, and Systems for Industrial and Scientific Applications XIV, 86590K (19 February 2013); doi: 10.1117/12.2006382; https://doi.org/10.1117/12.2006382
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