Grating-based dark-field breast imaging

Jens Rieger; Florian Bayer; Jürgen Durst; Karl Gödel; Wilhelm Haas; Florian Horn; Thilo Michel; Georg Pelzer; André Ritter; Thomas Weber; Andrea Zang; Gisela Anton

doi:10.1117/12.2007849

19 March 2013 Grating-based dark-field breast imaging

Jens Rieger, Florian Bayer, Jürgen Durst, Karl Gödel, Wilhelm Haas, Florian Horn, Thilo Michel, Georg Pelzer, André Ritter, Thomas Weber, Andrea Zang, Gisela Anton

Author Affiliations +

Proceedings Volume 8668, Medical Imaging 2013: Physics of Medical Imaging; 866810 (2013) https://doi.org/10.1117/12.2007849
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Grating-based X-ray phase-contrast imaging (XPCI) is a promising modality to increase soft-tissue contrast in medical imaging and especially in the case of mammography. Several groups worldwide have performed investigations on grating-based Talbot-Lau X-ray imaging of breast tissue, but in most cases focussed on the soft tissue contrast enhancement of the differential phase image. In this contribution, we present promising measurements with a Talbot-Lau interferometer of several mastectomy breast tissue samples especially focussed on the sensitivity of the dark-field signal of microcalcifications and with a comparable dose value to conventional mammography. We can present a contrast improvement for calcifications in surrounding breast tissue for the dark-field image by a factor of 10 related to the attenuation image.

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Jens Rieger, Florian Bayer, Jürgen Durst, Karl Gödel, Wilhelm Haas, Florian Horn, Thilo Michel, Georg Pelzer, André Ritter, Thomas Weber, Andrea Zang, and Gisela Anton "Grating-based dark-field breast imaging", Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 866810 (19 March 2013); https://doi.org/10.1117/12.2007849

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