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19 March 2013 Radiation dose reduction and CNR enhancement in C-arm cone beam CT
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Proceedings Volume 8668, Medical Imaging 2013: Physics of Medical Imaging; 86682S (2013)
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States
In this work we applied dose reduction using the prior image constrained compress sensing (DR-PICCS) method on a C-arm cone beam CT system. DR-PICCS uses a smoothed image as the prior image. After applying DRPICCS, the final image will have noise variance inherited from the prior image and spatial resolution from the projection data. In order to investigate the dose reduction of DR-PICCS, three different dose levels were used in C-arm scans of animal subjects using a Siemens Zeego C-arm system under an IACUC protocol. Image volumes were reconstructed using the standard FBP and DR-PICCS algorithms(total of 160 images). These images were randomly mixed and presented to three experienced interventional radiologists(each having more than twenty years reading experience) to review and score using a five-point scale. After statistical significance testing, the results show that DR-PICCS can achieve more than 60% dose reduction while keeping the same image quality. And if we compare FBP and DR-PICCS at the same dose level the results show that DR-PICCS will generate higher quality images.
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Kai Niu, Jie Tang, Kevin Royalty, Orhan Ozkan, Charles Strother, Beverly Aagaard-Kienitz, Kari A. Pulfer, and Guang-Hong Chen "Radiation dose reduction and CNR enhancement in C-arm cone beam CT", Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 86682S (19 March 2013);

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