6 March 2013 Investigating the optical diffusion capabilities of nanophosphors for use in medical imaging
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Proceedings Volume 8668, Medical Imaging 2013: Physics of Medical Imaging; 86683V (2013) https://doi.org/10.1117/12.2015263
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States
The quality of medical images can be characterized by the signal transfer properties of the x-ray converter. Various studies have previously investigated the influence of the detector configuration on the optimization of medical imaging systems. However, novel technologies related to new luminescent materials seem to be promising for further improvements in medical imaging instrumentation technology. The aim of this study was to investigate and optimize granular phosphor-based X-ray converters by examining different phosphor materials with grain size in the nano-scale (four different categories). Optical diffusion was simulated based on Mie scattering theory and the imaging performance was predicted using Monte Carlo simulation methods. The Modulation Transfer Function (MTF) of all cases were evaluated and compared. Results showed and analyzed the relation between phosphor intrinsic properties on optical diffusion. It was found that the resolution of the nanophosphor is directly affected by the optical parameters and becomes better for high values of light extinction factor and light absorption probability. In particular, the present study showed that the utilization of optimum optical parameters based on specific physical (refractive index, light wavelength) and structural (grain size, packing density) parameters enhance manufacturers in nanophopshor synthesis and preparation to follow particular configurations of nanophoshor composition. Finally, high optical modulation was accomplished employing grains of high refractive index and size close to 200 nm.
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P. F. Liaparinos, P. F. Liaparinos, I. S. Kandarakis, I. S. Kandarakis, "Investigating the optical diffusion capabilities of nanophosphors for use in medical imaging", Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 86683V (6 March 2013); doi: 10.1117/12.2015263; https://doi.org/10.1117/12.2015263

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