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13 March 2013Volume-preserving correction of non-rigid registrations for the investigation of pleural thickening growth
Pleural thickenings can be assessed using 3D CT-image data. A precise registration in the thickening regions is
required for a detailed investigation of the volumetric thickening growth and to algorithmically combine image
information from two points in time. For this purpose, a non-rigid registration, utilizing B-spline based deformations,
is applied. This kind of deformation is computationally efficient; however it might induce volumetric
compression in the image domain. For the assessment of growth, it is inevitable to guarantee volume-preservation.
In this paper we suggest a new method to enforce this preservation during the registration process in selected image
regions. In contrast to other volume-preserving approaches, this correction is independent of the preliminary
chosen method to estimate the non-rigid registration. To reduce complexity in large scale cases, we additionally
present a method to approximate the global correction by successively solving smaller sub-tasks. Finally we
show that both methods reduce the compression induced by the deformation and also enhance the registration
quality in terms of image similarity.
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Peter Faltin, Thomas Kraus, Kraisorn Chaisaowong, "Volume-preserving correction of non-rigid registrations for the investigation of pleural thickening growth," Proc. SPIE 8669, Medical Imaging 2013: Image Processing, 86692R (13 March 2013);