29 March 2013 Porcine pulmonary artery distension during static pressure inflation
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Abstract
To improve the definition of the geometrical and mechanical properties of the porcine pulmonary arteries, we utilized an in vivo imaging-based approach to quantify the influence of static extravascular pressure change on pulmonary arterial geometry. The cross-sectional area and distance from the inlet of pulmonary arteries of two animals were measured over a range of static airway inflation pressure (7 cmH2O - 25 cmH2O, i.e. 0.69 kPa – 2.45 kPa). Vessels with diameter range of approximately 2.0 mm to 5.5 mm at airway inflation pressure of 25 cmH2O (2.45kPa) were considered. The results suggest that lung inflation stretches the vessels laterally, but has no statistically significant effect on diameter.
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Yik Ching Lee, Yik Ching Lee, Alys Clark, Alys Clark, Mathew Fuld, Mathew Fuld, Susan Haynes, Susan Haynes, Abhay Divekar, Abhay Divekar, Eric Hoffman, Eric Hoffman, Merryn Tawhai, Merryn Tawhai, } "Porcine pulmonary artery distension during static pressure inflation", Proc. SPIE 8672, Medical Imaging 2013: Biomedical Applications in Molecular, Structural, and Functional Imaging, 867208 (29 March 2013); doi: 10.1117/12.2006695; https://doi.org/10.1117/12.2006695
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