29 March 2013 Breast imaging with the SoftVue imaging system: first results
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For women with dense breast tissue, who are at much higher risk for developing breast cancer, the performance of mammography is at its worst. Consequently, many early cancers go undetected when they are the most treatable. Improved cancer detection for women with dense breasts would decrease the proportion of breast cancers diagnosed at later stages, which would significantly lower the mortality rate. The emergence of whole breast ultrasound provides good performance for women with dense breast tissue, and may eliminate the current trade-off between the cost effectiveness of mammography and the imaging performance of more expensive systems such as magnetic resonance imaging. We report on the performance of SoftVue, a whole breast ultrasound imaging system, based on the principles of ultrasound tomography. SoftVue was developed by Delphinus Medical Technologies and builds on an early prototype developed at the Karmanos Cancer Institute. We present results from preliminary testing of the SoftVue system, performed both in the lab and in the clinic. These tests aimed to validate the expected improvements in image performance. Initial qualitative analyses showed major improvements in image quality, thereby validating the new imaging system design. Specifically, SoftVue’s imaging performance was consistent across all breast density categories and had much better resolution and contrast. The implications of these results for clinical breast imaging are discussed and future work is described.
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Neb Duric, Neb Duric, Peter Littrup, Peter Littrup, Steven Schmidt, Steven Schmidt, Cuiping Li, Cuiping Li, Olivier Roy, Olivier Roy, Lisa Bey-Knight, Lisa Bey-Knight, Roman Janer, Roman Janer, Dave Kunz, Dave Kunz, Xiaoyang Chen, Xiaoyang Chen, Jeffrey Goll, Jeffrey Goll, Andrea Wallen, Andrea Wallen, Fouzaan Zafar, Fouzaan Zafar, Veerendra Allada, Veerendra Allada, Erik West, Erik West, Ivana Jovanovic, Ivana Jovanovic, Kuo Li, Kuo Li, William Greenway, William Greenway, } "Breast imaging with the SoftVue imaging system: first results", Proc. SPIE 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy, 86750K (29 March 2013); doi: 10.1117/12.2002513; https://doi.org/10.1117/12.2002513

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