26 February 2013 Modeling of a single red blood cell thermal reaction exposed to infrared laser tweezers
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Proceedings Volume 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV; 86990P (2013) https://doi.org/10.1117/12.2016846
Event: Saratov Fall Meeting and Workshop on Laser Physics and Photonics 2012, 2012, Saratov, Russian Federation
Abstract
Continuous-wave laser micro-beams are generally used as diagnostic tools in laser scanning microscopes or in the case of near-infrared (NIR) micro-beams, as optical traps for cell manipulation and force characterization. Because single beam traps are created with objectives of high numerical aperture, typical trapping intensities and photon flux densities are in the order of 106 W/cm2 and 103 cm-2s-1, respectively. The main idea of our theoretical study was to investigate the thermal reaction of RBCs irradiated by laser micro-beam. The study is supported by the fact that many experiments have been carried out with RBCs in laser NIR tweezers. In the present work it has been identified that the laser affects a RBC with a density of absorbed energy at approximately 107 J/cm3, which causes a temperature rise in the cell of about 7 – 12 °C.
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A. Seteikin, A. Seteikin, I. Krasnikov, I. Krasnikov, I. Bernhardt, I. Bernhardt, } "Modeling of a single red blood cell thermal reaction exposed to infrared laser tweezers", Proc. SPIE 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV, 86990P (26 February 2013); doi: 10.1117/12.2016846; https://doi.org/10.1117/12.2016846
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