A hybrid plasmonic whispering gallery mode sensor for single bionanoparticle detection

S. Holler; V. R. Dantham; V. Kolchenko; Z. Wan; S. Arnold

doi:10.1117/12.2015506

29 May 2013 A hybrid plasmonic whispering gallery mode sensor for single bionanoparticle detection

S. Holler, V. R. Dantham, V. Kolchenko, Z. Wan, S. Arnold

Proceedings Volume 8722, Fiber Optic Sensors and Applications X; 87220T (2013) https://doi.org/10.1117/12.2015506
Event: SPIE Defense, Security, and Sensing, 2013, Baltimore, Maryland, United States

Abstract

Our hybrid plasmonic whispering gallery mode biosensor has recently demonstrated detection and characterization of the smallest known RNA virus. A gold nanoparticle affixed to the resonator surface acts like a nanoscopic antenna, enhancing locally the electric field within the cavity mode. When a target analyte binds with this nanoscopic antenna the result is an enhanced response (spectral shift) of the resonator system to the binding event. We have observed shift enhancements ~70× over the response of the bare resonator, thereby permitting the detection and characterization of all known viral particles and even some large protein molecules.

Citation Download Citation

S. Holler, V. R. Dantham, V. Kolchenko, Z. Wan, and S. Arnold "A hybrid plasmonic whispering gallery mode sensor for single bionanoparticle detection", Proc. SPIE 8722, Fiber Optic Sensors and Applications X, 87220T (29 May 2013); https://doi.org/10.1117/12.2015506

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