7 May 2013 Small-scale laser based electron accelerators for biology and medicine: a comparative study of the biological effectiveness
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Abstract
Laser-driven electron accelerators based on the Laser Wakefield Acceleration process has entered a mature phase to be considered as alternative devices to conventional radiofrequency linear accelerators used in medical applications. Before entering the medical practice, however, deep studies of the radiobiological effects of such short bunches as the ones produced by laser-driven accelerators have to be performed. Here we report on the setup, characterization and first test of a small-scale laser accelerator for radiobiology experiments. A brief description of the experimental setup will be given at first, followed by an overview of the electron bunch characterization, in particular in terms of dose delivered to the samples. Finally, the first results from the irradiation of biological samples will be briefly discussed.
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Luca Labate, Luca Labate, Maria Grazia Andreassi, Maria Grazia Andreassi, Federica Baffigi, Federica Baffigi, Giuseppina Basta, Giuseppina Basta, Ranieri Bizzarri, Ranieri Bizzarri, Andrea Borghini, Andrea Borghini, Giuliana Carmela Candiano, Giuliana Carmela Candiano, Carlo Casarino, Carlo Casarino, Monica Cresci, Monica Cresci, Fabio Di Martino, Fabio Di Martino, Lorenzo Fulgentini, Lorenzo Fulgentini, Francesco Ghetti, Francesco Ghetti, Maria Carla Gilardi, Maria Carla Gilardi, Antonio Giulietti, Antonio Giulietti, Petra Köster, Petra Köster, Francesco Lenci, Francesco Lenci, Tadzio Levato, Tadzio Levato, Yuji Oishi, Yuji Oishi, Giorgio Russo, Giorgio Russo, Antonella Sgarbossa, Antonella Sgarbossa, Claudio Traino, Claudio Traino, Leonida A. Gizzi, Leonida A. Gizzi, } "Small-scale laser based electron accelerators for biology and medicine: a comparative study of the biological effectiveness", Proc. SPIE 8779, Laser Acceleration of Electrons, Protons, and Ions II; and Medical Applications of Laser-Generated Beams of Particles II; and Harnessing Relativistic Plasma Waves III, 87790O (7 May 2013); doi: 10.1117/12.2019689; https://doi.org/10.1117/12.2019689
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