18 November 2013 A diffuse reflectance spectroscopy system to study biological tissues
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Proceedings Volume 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications; 8785E8 (2013) https://doi.org/10.1117/12.2026477
Event: 8th Ibero American Optics Meeting/11th Latin American Meeting on Optics, Lasers, and Applications, 2013, Porto, Portugal
Abstract
Diffuse reflectance spectroscopy (DRS) is a technique that allows the study of the structural and biochemical condition of tissues in a noninvasive-nonionizing way. DRS has been widely used in biomedical applications, mainly as an alternative to biopsy. Generally, the technique consists in the irradiation of a specific zone of a tissue with a reference spectrum. Then, the reemitted by the tissue light is detected. The changes suffered by the backscattered spectrum (after light-tissue interaction) with respect to the incident one carry information about the tissue properties. This work presents a novel system designed and developed to use DRS in biomedical applications. The system uses a LED as a light source and a specially designed optical fiber probe as a mean to deliver the light to the tissue surface, and to collect the reemitted photons from the studied sample. This probe was designed to accomplish two different tasks: to increase the sensitivity of the diagnosis; and to study the radial dependence of the backscattered light. The measuring probe was built in a way that allows taking readings when the exerted pressure on the tissue reaches certain predetermined values.
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A. de la Cadena, S. Stolik, J. M. de la Rosa, "A diffuse reflectance spectroscopy system to study biological tissues", Proc. SPIE 8785, 8th Iberoamerican Optics Meeting and 11th Latin American Meeting on Optics, Lasers, and Applications, 8785E8 (18 November 2013); doi: 10.1117/12.2026477; https://doi.org/10.1117/12.2026477
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