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17 June 2013 Dual mode fibre bundle confocal endomicroscopy: combining reflectance and fluorescence imaging
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Abstract
Commercial endomicroscopes operate in fluorescence mode only and so require the application of contrast agents. As an alternative, we describe a fibre bundle confocal endomicroscope which acquires simultaneous and co-registered fluorescence and reflectance mode images. A combination of polarisation selection and refractive index matching is used to minimise back-reflections from the fibre bundle. We show preliminary results from the system using phantoms and tissue samples.
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Michael Hughes, Vasiliki Simaiaki, Tou Pin Chang, and Guang-Zhong Yang "Dual mode fibre bundle confocal endomicroscopy: combining reflectance and fluorescence imaging ", Proc. SPIE 8797, Advanced Microscopy Techniques III, 879708 (17 June 2013); https://doi.org/10.1117/12.2032551
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