Development and evaluation of a multislice fluorescence molecular tomography using finite element method

Marjaneh Hejazi; Saeed Sarkar; Hanieh Mohammadreza; Toktam Jahanfar; Mansoureh Karimi

doi:10.1117/12.2032441

14 June 2013 Development and evaluation of a multislice fluorescence molecular tomography using finite element method

Marjaneh Hejazi, Saeed Sarkar, Hanieh Mohammadreza, Toktam Jahanfar, Mansoureh Karimi

Author Affiliations +

Proceedings Volume 8799, Diffuse Optical Imaging IV; 87990R (2013) https://doi.org/10.1117/12.2032441
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

Fluorescence molecular tomography is a novel approach that allows small animal imaging for early detection of cancer. However, challenges still remain in the improvement of the FMT software and hardware. In this work, a multislice FMT imaging system was developed and a finite element software with the modified calibration method was adapted to the geometry system. Phantom experiments are performed to verify the feasibility of the proposed method. The results demonstrate that the spatial resolution of the imaging system is less than 0.5mm and acquisition data time 30 minutes. In conclusion, The FMT system is capable to quantify 3D dye distribution using the well documented finite element software. OCIS codes: 110.6960, 170.3660

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Marjaneh Hejazi, Marjaneh Hejazi, Saeed Sarkar, Saeed Sarkar, Hanieh Mohammadreza, Hanieh Mohammadreza, Toktam Jahanfar, Toktam Jahanfar, Mansoureh Karimi, Mansoureh Karimi, "Development and evaluation of a multislice fluorescence molecular tomography using finite element method", Proc. SPIE 8799, Diffuse Optical Imaging IV, 87990R (14 June 2013); doi: 10.1117/12.2032441; https://doi.org/10.1117/12.2032441

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