Temperature controlled retinal photocoagulation

Kerstin Schlott; Stefan Koinzer; Alexander Baade; Reginald Birngruber; Johann Roider; Ralf Brinkmann

doi:10.1117/12.2033416

14 June 2013 Temperature controlled retinal photocoagulation

Kerstin Schlott, Stefan Koinzer, Alexander Baade, Reginald Birngruber, Johann Roider, Ralf Brinkmann

Proceedings Volume 8800, Opto-Acoustic Methods and Applications; 880009 (2013) https://doi.org/10.1117/12.2033416
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

Retinal photocoagulation lacks objective dosage in clinical use, thus the commonly applied lesions are too deep and strong, associated with pain reception and the risk of visual field defects and induction of choroidal neovascularisations. Optoacoustics allows real-time non-invasive temperature measurement in the fundus during photocoagulation by applying short probe laser pulses additionally to the treatment radiation, which excite the emission of ultrasonic waves. Due to the temperature dependence of the Grüneisen parameter, the amplitudes of the ultrasonic waves can be used to derive the temperature of the absorbing tissue. By measuring the temperatures in real-time and automatically controlling the irradiation by feedback to the treatment laser, the strength of the lesions can be defined. Different characteristic functions for the time and temperature dependent lesion sizes were used as rating curves for the treatment laser, stopping the irradiation automatically after a desired lesion size is achieved. The automatically produced lesion sizes are widely independent of the adjusted treatment laser power and individual absorption. This study was performed on anaesthetized rabbits and is a step towards a clinical trial with automatically controlled photocoagulation.

Citation Download Citation

Kerstin Schlott, Stefan Koinzer, Alexander Baade, Reginald Birngruber, Johann Roider, and Ralf Brinkmann "Temperature controlled retinal photocoagulation", Proc. SPIE 8800, Opto-Acoustic Methods and Applications, 880009 (14 June 2013); https://doi.org/10.1117/12.2033416

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