Photoacoustic stability of gold nanorods embedded in biopolymeric scaffolds

Lucia Cavigli; Marella De Angelis; Fulvio Ratto; Paolo Matteini; Francesca Rossi; Francesca Tatini; Sonia Centi; Roberto Pini

doi:10.1117/12.2032546

14 June 2013 Photoacoustic stability of gold nanorods embedded in biopolymeric scaffolds

Lucia Cavigli, Marella De Angelis, Fulvio Ratto, Paolo Matteini, Francesca Rossi, Francesca Tatini, Sonia Centi, Roberto Pini

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Proceedings Volume 8800, Opto-Acoustic Methods and Applications; 88000E (2013) https://doi.org/10.1117/12.2032546
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

Gold nanorods exhibit intense optical absorbance in the near-infrared window of principal interest for applications in biomedical optics making them appealing as contrast agents in photoacoustic imaging and selective photothermolysis of cancer. However their photoinstability under laser irradiation remains a drawback of practical concern. In particular, when GNRs are irradiated with nanosecond laser pulses in resonance with their plasmon oscillations, there may occur phenomena like reshaping into spherical particles, as well as fragmentation at higher optical fluences, which result into modifications of their optical absorption bands and substantial loss of photoacoustic conversion efficiency.

In this contribution we present an investigation of the photostability of gold nanorods embedded in biomimetic scaffolds by means of photoacustic experiments.

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Lucia Cavigli, Marella De Angelis, Fulvio Ratto, Paolo Matteini, Francesca Rossi, Francesca Tatini, Sonia Centi, and Roberto Pini "Photoacoustic stability of gold nanorods embedded in biopolymeric scaffolds", Proc. SPIE 8800, Opto-Acoustic Methods and Applications, 88000E (14 June 2013); https://doi.org/10.1117/12.2032546

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KEYWORDS

Photoacoustic spectroscopy

Biomedical optics

Gold

Nanorods

Particles

Absorption

Plasmons

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