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24 June 2013Simultaneous imaging of cortical haemoglobin concentration and blood flow with RGB reflectometry and LASCA during cortical activation in rats
We demonstrate the simultaneous imaging of cortical blood flow and haemoglobin oxygenation of the exposed cortex in rats using laser speckle contrast analysis (LASCA) and RGB reflectometry. Spatial and temporal resolved changes in blood flow and oxygenation are observed for single forepaw stimulation.
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A. Steimers, S. Pinkernell, U. Lindauer, M. Kohl-Bareis, "Simultaneous imaging of cortical haemoglobin concentration and blood flow with RGB reflectometry and LASCA during cortical activation in rats," Proc. SPIE 8804, Neurophotonics, 880403 (24 June 2013);