Laser polarization fluorescence of optically anisotropic crystals molecular imaging in the differentiation of biological
benign and malignant tumors

Yu. A. Ushenko; A. V. Dubolazov; A. O. Karachevtsev; A. V. Motrich; M. I. Sidor

doi:10.1117/12.2023689

11 September 2013 Laser polarization fluorescence of optically anisotropic crystals molecular imaging in the differentiation of biological benign and malignant tumors

Yu. A. Ushenko, A. V. Dubolazov, A. O. Karachevtsev, A. V. Motrich, M. I. Sidor

Author Affiliations +

Proceedings Volume 8812, Biosensing and Nanomedicine VI; 88120Z (2013) https://doi.org/10.1117/12.2023689
Event: SPIE NanoScience + Engineering, 2013, San Diego, California, United States

Abstract

The model of laser polarization fluorescence of biological tissues considering the mechanisms of optically anisotropic absorption – linear and circular dichroism of protein networks was suggested.Muellermatrix rotation invariants characterizing polarization manifestations of laser fluorescence are determined.The interconnections between the statistical, correlation and fractal parameters characterizing the Mueller-matrix images of laser polarization fluorescence and the peculiarities of the mechanisms of optically anisotropic absorption of histological sections of uterus wall biopsy were found. Effectiveness of the method of azimuthinvariant Mueller-matrix mapping of laser polarization fluorescence of protein networks in the task of differentiation of benign and malignant tumors of uterus wall was demonstrated.

Citation Download Citation

Yu. A. Ushenko, A. V. Dubolazov, A. O. Karachevtsev, A. V. Motrich, and M. I. Sidor "Laser polarization fluorescence of optically anisotropic crystals molecular imaging in the differentiation of biological benign and malignant tumors", Proc. SPIE 8812, Biosensing and Nanomedicine VI, 88120Z (11 September 2013); https://doi.org/10.1117/12.2023689

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