Real-time measurement with a fiber optical surface plasmon resonance sensor for biochemical interaction analysis

Zhixin Tan; Xuejin Li; Yuzhi Chen; Ping Fan

doi:10.1117/12.2031813

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29 August 2013 Real-time measurement with a fiber optical surface plasmon resonance sensor for biochemical interaction analysis

Zhixin Tan, Xuejin Li, Yuzhi Chen, Ping Fan

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Proceedings Volume 8914, International Symposium on Photoelectronic Detection and Imaging 2013: Fiber Optic Sensors and Optical Coherence Tomography; 891406 (2013) https://doi.org/10.1117/12.2031813
Event: ISPDI 2013 - Fifth International Symposium on Photoelectronic Detection and Imaging, 2013, Beijing, China

Abstract

In this paper we report a fiber optical sensor system based on surface plasmon resonance (SPR) with real-time response for biochemical interaction analysis. The fiber sensor is constructed from a multi-mode fiber with plastic cladding. To facilitate the measurement, a software program is developed which integrates the data acquisition and processing for real-time feedback. Polynomial fitting is implemented to smooth out the noise in the transmission ratio and a spectral resolution of 0.2 nm is achieved. Ethyl alcohol and water mixtures with different concentrations are measured to demonstrate the system's real-time capability. This work is essential for the development of a compact, real-time fiber SPR biosensor.

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Zhixin Tan, Xuejin Li, Yuzhi Chen, and Ping Fan "Real-time measurement with a fiber optical surface plasmon resonance sensor for biochemical interaction analysis", Proc. SPIE 8914, International Symposium on Photoelectronic Detection and Imaging 2013: Fiber Optic Sensors and Optical Coherence Tomography, 891406 (29 August 2013); https://doi.org/10.1117/12.2031813

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