Blood coagulation using High Intensity Focused Ultrasound (HIFU)

Phuc V. Nguyen; Junghwan Oh; Hyun Wook Kang

doi:10.1117/12.2037171

4 March 2014 Blood coagulation using High Intensity Focused Ultrasound (HIFU)

Phuc V. Nguyen, Junghwan Oh, Hyun Wook Kang

Proceedings Volume 8926, Photonic Therapeutics and Diagnostics X; 89261A (2014) https://doi.org/10.1117/12.2037171
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

High Intensity Focused Ultrasound (HIFU) technology provides a feasible method of achieving thermal coagulation during surgical procedures. One of the potential clinical benefits of HIFU can induce immediate hemostasis without suturing. The objective of this study was to investigate the efficiency of a HIFU system for blood coagulation on severe vascular injury. HIFU treatment was implemented immediately after bleeding in artery. The ultrasound probe was made of piezoelectric material, generating a central frequency of 2.0 MHz as well as an ellipsoidal focal spot of 2 mm in lateral dimension and 10 mm in axial dimension. Acoustic coagulation was employed on a perfused chicken artery model in vitro. A surgical incision (1 to 2 mm long) was made with a scapel on the arterial wall, and heparinized autologous blood was made to leak out from the incision with a syringe pump. A total of 5 femoral artery incisions was treated with the HIFU beam. The intensity of 4500 W/cm² at the focus was applied for all treatments. Complete hemostasis was achieved in all treatments, along with the treatment times of 25 to 50 seconds. The estimated intraoperative blood loss was from 2 to 5 mL. The proposed HIFU system may provide an effective method for immediate blood coagulation for arteries and veins in clinical applications.

Citation Download Citation

Phuc V. Nguyen, Junghwan Oh, and Hyun Wook Kang "Blood coagulation using High Intensity Focused Ultrasound (HIFU)", Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 89261A (4 March 2014); https://doi.org/10.1117/12.2037171

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KEYWORDS

Arteries

Blood

Acoustics

Transducers

Tissues

Ultrasonography

Blood vessels

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