Infrared fiber optic probes for evaluation of musculoskeletal tissue pathology

Mugdha Padalkar; Cushla McGoverin; Quam Onigbanjo; Richard Spencer; Scott Barbash; Eric Kropf; Nancy Pleshko

doi:10.1117/12.2047473

4 March 2014 Infrared fiber optic probes for evaluation of musculoskeletal tissue pathology

Mugdha Padalkar, Cushla McGoverin, Quam Onigbanjo, Richard Spencer, Scott Barbash, Eric Kropf, Nancy Pleshko

Proceedings Volume 8926, Photonic Therapeutics and Diagnostics X; 89263Y (2014) https://doi.org/10.1117/12.2047473
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Musculoskeletal pathology of the knee commonly occurs with aging and as a result of injury. The incidence of anterior cruciate ligament (ACL) injuries continues to increase annually, and may precede the eventual onset of osteoarthritis (OA), a debilitating and prevalent disease characterized by cartilage degeneration. Early detection of OA remains elusive, with current imaging methods lacking adequate sensitivity to detect early pathologic cartilage changes. We used mid- and near- infrared (IR) spectroscopy through arthroscopic-based fiber-optic devices to assess cartilage damage and differentiate tendon from ligament. Mid-IR spectroscopy is characterized by distinct bands and low penetration depth (< 10 μm) and near-IR spectroscopy is characterized by complex overlapping bands and greater penetration depths (< 1 cm). We have found that combined mid- and near-IR analysis greatly extends the information available through either in the analysis of soft tissues, including cartilage, ligaments and tendons. We discuss here basic science studies and the potential for translation to clinical research with novel arthroscopic probes.

Citation Download Citation

Mugdha Padalkar, Cushla McGoverin, Quam Onigbanjo, Richard Spencer, Scott Barbash, Eric Kropf, and Nancy Pleshko "Infrared fiber optic probes for evaluation of musculoskeletal tissue pathology", Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 89263Y (4 March 2014); https://doi.org/10.1117/12.2047473

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KEYWORDS

Near infrared

Mid-IR

Cartilage

Fiber optics

Tissues

Near infrared spectroscopy

Infrared radiation

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