28 February 2014 Air-puff OCE for assessment of mouse cornea in vivo
Author Affiliations +
Proceedings Volume 8930, Ophthalmic Technologies XXIV; 893004 (2014) https://doi.org/10.1117/12.2042258
Event: SPIE BiOS, 2014, San Francisco, California, United States
Abstract
We characterize the relaxation rates of deformations created by focused air puffs with the use of phasestabilized swept source optical coherence elastography (PhS-SSOCE) in tissue-mimicking gelatin phantoms of various concentrations and mouse corneas of different ages in vivo. The results indicate that gelatin of varying concentrations and corneas from different aged mice have different relaxation rates. In addition, the results show that phantoms with higher concentration gelatin and corneas of older mice have higher relaxation rates, which can be attributed to stiffer material. Because this method is non-contact, noninvasive, and utilizes a minimal force which induces a deformation on the scale of μm, this method can be used to study the biomechanical properties of sensitive tissues, such as the cornea.
© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Jiasong Li, Jiasong Li, Shang Wang, Shang Wang, Manmohan Singh, Manmohan Singh, Salavat Aglyamov, Salavat Aglyamov, Stanislav Emelianov, Stanislav Emelianov, Michael Twa, Michael Twa, Kirill V. Larin, Kirill V. Larin, } "Air-puff OCE for assessment of mouse cornea in vivo", Proc. SPIE 8930, Ophthalmic Technologies XXIV, 893004 (28 February 2014); doi: 10.1117/12.2042258; https://doi.org/10.1117/12.2042258
PROCEEDINGS
5 PAGES


SHARE
Back to Top