Translator Disclaimer
28 February 2014 Novel technique: a pupillometer-based objective chromatic perimetry
Author Affiliations +
Proceedings Volume 8930, Ophthalmic Technologies XXIV; 89300G (2014)
Event: SPIE BiOS, 2014, San Francisco, California, United States
Evaluation of visual field (VF) is important for clinical diagnosis and patient monitoring. The current VF methods are subjective and require patient cooperation. Here we developed a novel objective perimetry technique based on the pupil response (PR) to multifocal chromatic stimuli in normal subjects and in patients with glaucoma and retinitis pigmentosa (RP). A computerized infrared video pupillometer was used to record PR to short- and long-wavelength stimuli (peak 485 nm and 620 nm, respectively) at light intensities of 15-100 cd-s/m2 at thirteen different points of the VF. The RP study included 30 eyes of 16 patients and 20 eyes of 12 healthy participants. The glaucoma study included 22 eyes of 11 patients and 38 eyes of 19 healthy participants. Significantly reduced PR was observed in RP patients in response to short-wavelength stimuli at 40 cd-s/m2 in nearly all perimetric locations (P <0.05). By contrast, RP patients demonstrated nearly normal PR to long-wavelength in majority of perimetric locations. The glaucoma group showed significantly reduced PR to long- and short-wavelength stimuli at high intensity in all perimetric locations (P <0.05). The PR of glaucoma patients was significantly lower than normal in response to short-wavelength stimuli at low intensity mostly in central and 20° locations (p<0.05). This study demonstrates the feasibility of using pupillometer-based chromatic perimetry for objectively assessing VF defects and retinal function and optic nerve damage in patients with retinal dystrophies and glaucoma. Furthermore, this method may be used to distinguish between the damaged cells underlying the VF defect.
© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ygal Rotenstreich, Alon Skaat, Ifat Sher, Andru Kolker, Elkana Rosenfeld, Shlomo Melamed, and Michael Belkin "Novel technique: a pupillometer-based objective chromatic perimetry", Proc. SPIE 8930, Ophthalmic Technologies XXIV, 89300G (28 February 2014);


The Eye As A Detector
Proceedings of SPIE (June 01 1971)
From light to optic nerve optimization of the front...
Proceedings of SPIE (April 21 1998)
Color assimilation and contrast near absolute threshold
Proceedings of SPIE (January 24 2012)
Analysis of the standard colorimetric observer
Proceedings of SPIE (August 14 2001)

Back to Top