This PDF file contains the front matter associated with SPIE Proceedings Volume 8931, including the Title Page, Copyright information, Table of Contents, Invited Panel Discussion, and Conference Committee listing.

The papers included in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. The papers published in these proceedings reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon.

Please use the following format to cite material from this book:

Author(s), “Title of Paper,” in Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIII, edited by David H. Kessel, Tayyaba Hasan, Proceedings of SPIE Vol. 8931 (SPIE, Bellingham, WA, 2014) Article CID Number.

ISSN: 1605-7422

ISBN: 9780819498441

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Paper Numbering: Proceedings of SPIE follow an e-First publication model, with papers published first online and then in print and on CD-ROM. Papers are published as they are submitted and meet publication criteria. A unique, consistent, permanent citation identifier (CID) number is assigned to each article at the time of the first publication. Utilization of CIDs allows articles to be fully citable as soon as they are published online, and connects the same identifier to all online, print, and electronic versions of the publication. SPIE uses a six-digit CID article numbering system in which:

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Conference Committee

Symposium Chairs

  • James G. Fujimoto, Massachusetts Institute of Technology (United States)

  • R. Rox Anderson, Wellman Center for Photomedicine, Massachusetts General Hospital (United States) and Harvard School of Medicine (United States)

Program Track Chair

  • Brian Jet-Fei Wong, Beckman Laser Institute and Medical Clinic (United States)

Conference Chairs

  • David H. Kessel, Wayne State University (United States)

  • Tayyaba Hasan, Massachusetts General Hospital (United States)

Conference Program Committee

  • Charles J. Gomer, Children’s Hospital Los Angeles (United States)

  • Nancy L. Oleinick, Case Western Reserve University (United States)

  • Ravindra K. Pandey, Roswell Park Cancer Institute (United States)

  • Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States)

  • Kenneth K. Wang M.D., Mayo Clinic (United States)

Session Chairs

  • 1 Photodynamic Therapy I

    David H. Kessel, Wayne State University (United States)

  • 2 Photodynamic Therapy II

    Tayyaba Hasan, Massachusetts General Hospital (United States)

  • 3 Photodynamic Therapy III

    Imran Rizvi, Massachusetts General Hospital (United States)

    Jonathan P. Celli, University of Massachusetts (United States)

  • 4 Photodynamic Therapy IV

    Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States)

  • 5 Photodynamic Therapy V

    Edward V. Maytin M.D., The Cleveland Clinic (United States)

    Merrill A. Biel M.D., University of Minnesota (United States)

  • 6 Photodynamic Therapy VI

    Kenneth K. Wang M.D., Mayo Clinic (United States)

    Keith A. Cengel, University of Pennsylvania School of Medicine (United States)

  • 7 Photodynamic Therapy VII

    Conor L. Evans, Wellman Center for Photomedicine (United States)

  • 8 Photodynamic Therapy VIII

    Charles W. Spangler, Rasiris, Inc. (United States)


SPIE has been holding conferences related to photodynamic therapy since 1987, and the topic now appears in conferences other than this one. While reports relating to technology and applications are not ruled out, contributions mainly relate to mechanism of action, pathways to photokilling and similar topics.

In the early days, PDT research was often concerned with identifying the components of the mysterious compound ‘HPD’, development of new and better light sources, working out exactly what happened when photosensitized tumors were irradiated and identifying clinical indications for PDT. More recently, research is being directed toward ‘third generation’ problems, e.g., what PDT can tell us about cell biology, and what effects photodamage can have far downstream from the initial interactions. Procedures involving 3D cell cultures and orthotopic tumor implants are bringing experimental techniques closer to accurate predictions for clinical outcomes.

Two concerns are currently limiting the impact PDT is having on health care. Pharmaceutical organizations in the PDT field have not been uniformly successful and have often made significant errors in marketing decisions. Research grants now depend on the perception of ‘impact’, and this can be affected by this perception. In this environment, it is perhaps remarkable that research into PDT and its applications still persists.

David H. Kessel

Tayyaba Hasan

© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
} "Front Matter: Volume 8931", Proc. SPIE 8931, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXIII, 893101 (18 March 2014); doi: 10.1117/12.2053606; https://doi.org/10.1117/12.2053606

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