18 February 2014 Wavelength, beam size and type dependences of cerebral low-level light therapy: A Monte Carlo study on visible Chinese human
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Proceedings Volume 8932, Mechanisms for Low-Light Therapy IX; 893209 (2014) https://doi.org/10.1117/12.2041875
Event: SPIE BiOS, 2014, San Francisco, California, United States
Abstract
Low level light therapy (LLLT) has been clinically utilized for many indications in medicine requiring protection from cell/tissue death, stimulation of healing and repair of injuries, pain reduction, swelling and inflammation. Presently, use of LLLT to treat stroke, traumatic brain injury, and cognitive dysfunction is attracting growing interest. Near-infrared light can penetrate into the brain tissue, allowing noninvasive treatment to be carried out with few treatment-related adverse events. Optimization of LLLT treatment effect is one key issue of the field; however, only a few experimental tests on mice for wavelength selection have been reported. We addressed this issue by low-cost, straightforward and quantitative comparisons on light dosage distribution in Visible Chinese human head with Monte Carlo modeling of light propagation. Optimized selection in wavelength, beam type and size were given based on comparisons among frequently-used setups (i.e., wavelengths: 660 nm, 810 nm, 980 nm; beam type: Gaussian and flat beam; beam diameter: 2 cm, 4 cm, 6cm).This study provided an efficient way to guide optimization of LLLT setup and selection on wavelength, beam type and size for clinical brain LLLT.
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Ting Li, Ting Li, Yue Zhao, Yue Zhao, Meixue Duan, Meixue Duan, Yunlong Sun, Yunlong Sun, Kai Li, Kai Li, } "Wavelength, beam size and type dependences of cerebral low-level light therapy: A Monte Carlo study on visible Chinese human", Proc. SPIE 8932, Mechanisms for Low-Light Therapy IX, 893209 (18 February 2014); doi: 10.1117/12.2041875; https://doi.org/10.1117/12.2041875
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