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13 March 2014 Label-free optical sensing on hybrid plasmonic-nanobiosilica platforms
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Diatoms are single-celled algaes that make photonic-crystal-like silica shells or frustules with hierarchical micro- and nano-scale features consisting of two-dimensional periodic pores. In this paper, we present an innovative label-free optical sensor based on a biological-plasmonic hybrid nanostructure by self-assembling silver (Ag) nanoparticles into diatom frustules. The photonic-crystal-like diatom frustules provide a spatially confined electric field with enhanced intensity that can form hybrid photonic-plasmonic modes through the optical coupling with Ag nanoparticles. The experimental results demonstrate 4-6x and 9-12x improvement of sensitivities to detect the Raman dye for resonance and nonresonance SERS sensing, respectively.
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Fanghui Ren, Jeremy Campbell, Gregory L. Rorrer, and Alan X. Wang "Label-free optical sensing on hybrid plasmonic-nanobiosilica platforms", Proc. SPIE 8933, Frontiers in Biological Detection: From Nanosensors to Systems VI, 89330J (13 March 2014);

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