4 March 2014 Imaging of the interaction of low frequency electric fields with biological tissues by optical coherence tomography
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Abstract
We report the use of conventional Optical Coherence Tomography (OCT) for visualization of propagation of low frequency electric field in soft biological tissues ex vivo. To increase the overall quality of the experimental images an adaptive Wiener filtering technique has been employed. Fourier domain correlation has been subsequently applied to enhance spatial resolution of images of biological tissues influenced by low frequency electric field. Image processing has been performed on Graphics Processing Units (GPUs) utilizing Compute Unified Device Architecture (CUDA) framework in the frequencydomain. The results show that variation in voltage and frequency of the applied electric field relates exponentially to the magnitude of its influence on biological tissue. The magnitude of influence is about twice more for fresh tissue samples in comparison to non-fresh ones. The obtained results suggest that OCT can be used for observation and quantitative evaluation of the electro-kinetic changes in biological tissues under different physiological conditions, functional electrical stimulation, and potentially can be used non-invasively for food quality control.
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Adrian F. Peña, Adrian F. Peña, Jack Devine, Jack Devine, Alexander Doronin, Alexander Doronin, Igor Meglinski, Igor Meglinski, } "Imaging of the interaction of low frequency electric fields with biological tissues by optical coherence tomography", Proc. SPIE 8934, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII, 89341C (4 March 2014); doi: 10.1117/12.2040842; https://doi.org/10.1117/12.2040842
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