4 March 2014 Back-to-back optical coherence tomography-ultrasound probe for co-registered three-dimensional intravascular imaging with real-time display
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Abstract
We have developed a novel integrated optical coherence tomography (OCT)-intravascular ultrasound (IVUS) probe, with a 1.5 mm-long rigid-part and 0.9 mm outer diameter, for real-time intracoronary imaging of atherosclerotic plaques and guiding interventional procedures. By placing the OCT ball lens and IVUS 45MHz single element transducer back-to-back at the same axial position, this probe can provide automatically co-registered, co-axial OCT-IVUS imaging. To demonstrate its capability, 3D OCT-IVUS imaging of a pig’s coronary artery in real-time displayed in polar coordinates, as well as images of two major types of advanced plaques in human cadaver coronary segments, was obtained using this probe and our upgraded system. Histology validation is also presented.
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Jiawen Li, Jiawen Li, Teng Ma, Teng Ma, Joseph Jing, Joseph Jing, Jun Zhang, Jun Zhang, Pranav M. Patel, Pranav M. Patel, K. Kirk Shung, K. Kirk Shung, Qifa Zhou, Qifa Zhou, Zhongping Chen, Zhongping Chen, } "Back-to-back optical coherence tomography-ultrasound probe for co-registered three-dimensional intravascular imaging with real-time display", Proc. SPIE 8934, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII, 893428 (4 March 2014); doi: 10.1117/12.2038270; https://doi.org/10.1117/12.2038270
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