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17 February 2014 Dental imaging using laminar optical tomography and micro CT
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Proceedings Volume 8937, Multimodal Biomedical Imaging IX; 89370P (2014)
Event: SPIE BiOS, 2014, San Francisco, California, United States
Dental lesions located in the pulp are quite difficult to identify based on anatomical contrast, and, hence, to diagnose using traditional imaging methods such as dental CT. However, such lesions could lead to functional and/or molecular optical contrast. Herein, we report on the preliminary investigation of using Laminar Optical Tomography (LOT) to image the pulp and root canals in teeth. LOT is a non-contact, high resolution, molecular and functional mesoscopic optical imaging modality. To investigate the potential of LOT for dental imaging, we injected an optical dye into ex vivo teeth samples and imaged them using LOT and micro-CT simultaneously. A rigid image registration between the LOT and micro-CT reconstruction was obtained, validating the potential of LOT to image molecular optical contrast deep in the teeth with accuracy, non-invasively. We demonstrate that LOT can retrieve the 3D bio-distribution of molecular probes at depths up to 2mm with a resolution of several hundred microns in teeth.
© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Feixiao Long, Mehmet S. Ozturk, Xavier Intes, and Shiva Kotha "Dental imaging using laminar optical tomography and micro CT", Proc. SPIE 8937, Multimodal Biomedical Imaging IX, 89370P (17 February 2014);

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