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17 February 2014 Time-resolved measurements in diffuse reflectance: effects of the instrument response function of different detection systems on the depth sensitivity
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Proceedings Volume 8937, Multimodal Biomedical Imaging IX; 893710 (2014) https://doi.org/10.1117/12.2036366
Event: SPIE BiOS, 2014, San Francisco, California, United States
Abstract
We demonstrate the loss of depth sensitivity induced by the instrument response function on reflectance time-resolved diffuse optical tomography through the comparison of 3 detection systems: on one hand a photomultiplier tube (PMT) and a hybrid PMT coupled with a time-correlated single-photon counting card and on the other hand a high rate intensified camera. We experimentally evaluate the depth sensitivity achieved for each detection module with an absorbing inclusion embedded in a turbid medium. The different interfiber distances of 5, 10 and 15 mm are considered. Finally, we determine a maximal depth reached for each detection system by using 3D tomographic reconstructions based on the Mellin-Laplace transform.
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Agathe Puszka, Anne Planat-Chrétien, Michel Berger, Lionel Hervé, and Jean-Marc Dinten "Time-resolved measurements in diffuse reflectance: effects of the instrument response function of different detection systems on the depth sensitivity", Proc. SPIE 8937, Multimodal Biomedical Imaging IX, 893710 (17 February 2014); https://doi.org/10.1117/12.2036366
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