Paper
17 February 2014 Combining 3D optical imaging and dual energy absorptiometry to measure three compositional components
Serghei Malkov, John Shepherd
Author Affiliations +
Proceedings Volume 8937, Multimodal Biomedical Imaging IX; 893714 (2014) https://doi.org/10.1117/12.2040903
Event: SPIE BiOS, 2014, San Francisco, California, United States
Abstract
We report on the design of the technique combining 3D optical imaging and dual-energy absorptiometry body scanning to estimate local body area compositions of three compartments. Dual-energy attenuation and body shape measures are used together to solve for the three compositional tissue thicknesses: water, lipid, and protein. We designed phantoms with tissue-like properties as our reference standards for calibration purposes. The calibration was created by fitting phantom values using non-linear regression of quadratic and truncated polynomials. Dual-energy measurements were performed on tissue-mimicking phantoms using a bone densitometer unit. The phantoms were made of materials shown to have similar x-ray attenuation properties of the biological compositional compartments. The components for the solid phantom were tested and their high energy/low energy attenuation ratios are in good correspondent to water, lipid, and protein for the densitometer x-ray region. The three-dimensional body shape was reconstructed from the depth maps generated by Microsoft Kinect for Windows. We used open-source Point Cloud Library and freeware software to produce dense point clouds. Accuracy and precision of compositional and thickness measures were calculated. The error contributions due to two modalities were estimated. The preliminary phantom composition and shape measurements are found to demonstrate the feasibility of the method proposed.
© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Serghei Malkov and John Shepherd "Combining 3D optical imaging and dual energy absorptiometry to measure three compositional components", Proc. SPIE 8937, Multimodal Biomedical Imaging IX, 893714 (17 February 2014); https://doi.org/10.1117/12.2040903
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Cited by 1 scholarly publication and 8 patents.
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KEYWORDS
Proteins

Signal attenuation

Calibration

Tissues

X-rays

3D image processing

3D metrology

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