Rapid hyperspectral imaging in the mid-infrared

N. Kröger; A. Egl; M. Engel; N. Gretz; K. Haase; I. Herpich; S. Neudecker; A. Pucci; A. Schönhals; W. Petrich

doi:10.1117/12.2041988

4 March 2014 Rapid hyperspectral imaging in the mid-infrared

N. Kröger, A. Egl, M. Engel, N. Gretz, K. Haase, I. Herpich, S. Neudecker, A. Pucci, A. Schönhals, W. Petrich

Proceedings Volume 8939, Biomedical Vibrational Spectroscopy VI: Advances in Research and Industry; 89390Z (2014) https://doi.org/10.1117/12.2041988
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Despite the successes of mid-infrared hyperspectral imaging in a research environment, progress in the migration of technology into the day-to-day clinical application is slow. Clinical acceptance may be improved if the spectroscopy would be faster and the infrared microscopes available at lower cost. Here we present first results of a fast, multi-scale mid-infrared microscopy setup which allows for the investigation of 10.6×11.7 mm² and 2.8×3.1mm² fields of view with a resolution of 23.0±3.5 μm and 9.4±1.8 μm, respectively. Tunable quantum cascade lasers in the wavenumber ranges of 1030-1090 cm^-1 and 1160-1320 cm^-1 serve as light sources. A vapor cell is used as a frequency reference during the rapid scanning. As far as the imaging is concerned, it is the high spectral power density of the quantum cascade laser which enables the use of a microbolometer array while still obtaining reasonable signal-to-noise ratios on each pixel. Hyperspectral images are taken in times which can be as low as 52s for the overall image acquisition including referencing.

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N. Kröger, A. Egl, M. Engel, N. Gretz, K. Haase, I. Herpich, S. Neudecker, A. Pucci, A. Schönhals, and W. Petrich "Rapid hyperspectral imaging in the mid-infrared", Proc. SPIE 8939, Biomedical Vibrational Spectroscopy VI: Advances in Research and Industry, 89390Z (4 March 2014); https://doi.org/10.1117/12.2041988

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