Diffusing-wave polarimetry for tissue diagnostics

Callum Macdonald; Alexander Doronin; Adrian F. Peña; Michael Eccles; Igor Meglinski

doi:10.1117/12.2038658

17 March 2014 Diffusing-wave polarimetry for tissue diagnostics

Callum Macdonald, Alexander Doronin, Adrian F. Peña, Michael Eccles, Igor Meglinski

Author Affiliations +

Proceedings Volume 8940, Optical Biopsy XII; 894007 (2014) https://doi.org/10.1117/12.2038658
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

We exploit the directional awareness of circularly and/or elliptically polarized light propagating within media which exhibit high numbers of scattering events. By tracking the Stokes vector of the detected light on the Poincar´e sphere, we demonstrate its applicability for characterization of anisotropy of scattering. A phenomenological model is shown to have an excellent agreement with the experimental data and with the results obtained by the polarization tracking Monte Carlo model, developed in house. By analogy to diffusing-wave spectroscopy we call this approach diffusing-wave polarimetry, and illustrate its utility in probing cancerous and non-cancerous tissue samplesin vitro for diagnostic purposes.

Citation Download Citation

Callum Macdonald, Callum Macdonald, Alexander Doronin, Alexander Doronin, Adrian F. Peña, Adrian F. Peña, Michael Eccles, Michael Eccles, Igor Meglinski, Igor Meglinski, "Diffusing-wave polarimetry for tissue diagnostics", Proc. SPIE 8940, Optical Biopsy XII, 894007 (17 March 2014); doi: 10.1117/12.2038658; https://doi.org/10.1117/12.2038658

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