26 February 2014 Monte Carlo simulation on the effect of contact pressure on in vivo NIRS measurement
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Abstract
NIRS analysis is considered to be a promising noninvasive detection technique. Existing research results show that optical properties of the human skin tissue will change with different contact pressures when contact survey mode is used for in vivo NIRS measurement. The impact of the contact pressure might be greater than the impact of glucose concentration on the spectral data of NIRS. The uncertainty caused by pressure in vivo, makes it extremely difficult to get the high SNR-spectrum. In this talk, the Monte Carlo simulation has been carried on under the condition of different contact pressure. Simulation results show that the diffused reflectance and transmittance increase with rising contact pressure. Moreover, the simulation results show that the effects of contact pressure are larger than the effects of glucose concentration. Therefore it is promising to make comprehensive utilization of diffused reflectance and transmittance to eliminate the interference which caused by contact pressure.
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Jingying Jiang, Junsheng Lu, Hao Zhang, Xuzheng Rong, Zhenhe Ma, Kexin Xu, "Monte Carlo simulation on the effect of contact pressure on in vivo NIRS measurement", Proc. SPIE 8942, Dynamics and Fluctuations in Biomedical Photonics XI, 89420Y (26 February 2014); doi: 10.1117/12.2036891; https://doi.org/10.1117/12.2036891
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