3 March 2014 High-throughput fiber-array transvaginal ultrasound/photoacoustic probe for ovarian cancer imaging
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Abstract
A high-throughput ultrasound/photoacoustic probe for delivering high contrast and signal-to-noise ratio images was designed, constructed, and tested. The probe consists of a transvaginal ultrasound array integrated with four 1mm-core optical fibers and a sheath. The sheath encases transducer and is lined with highly reflecting aluminum for high intensity light output and uniformity while at the same time remaining below the maximum permissible exposure (MPE) recommended by the American National Standards Institute (ANSI). The probe design was optimized by simulating the light fluence distribution in Zemax. The performance of the probe was evaluated by experimental measurements of the fluence and real-time imaging of polyethylene-tubing filled with blood. These results suggest that our probe has great potential for in vivo imaging and characterization of ovarian cancer.
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Hassan S. Salehi, Patrick D. Kumavor, Umar Alqasemi, Hai Li, Tianheng Wang, Quing Zhu, "High-throughput fiber-array transvaginal ultrasound/photoacoustic probe for ovarian cancer imaging", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 894335 (3 March 2014); doi: 10.1117/12.2037082; https://doi.org/10.1117/12.2037082
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