3 March 2014 Accuracy of approximate inversion schemes in quantitative photoacoustic imaging
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Five numerical phantoms were developed to investigate the accuracy of approximate inversion schemes in the reconstruction of oxygen saturation in photoacoustic imaging. In particular, two types of inversion are considered: Type I, an inversion that assumes fluence is unchanged between illumination wavelengths, and Type II, a method that assumes known background absorption and scattering coefficients to partially correct for the fluence. These approaches are tested in tomography (PAT) and acoustic-resolution microscopy mode (AR-PAM). They are found to produce accurate values of oxygen saturation in a blood vessel of interest at shallow depth - less than 3mm for PAT and less than 1mm for AR-PAM.
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Roman Hochuli, Roman Hochuli, Paul C. Beard, Paul C. Beard, Ben Cox, Ben Cox, } "Accuracy of approximate inversion schemes in quantitative photoacoustic imaging", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 89435V (3 March 2014); doi: 10.1117/12.2039825; https://doi.org/10.1117/12.2039825

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