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27 February 2014 Special antitumor immune effects of laser immunotherapy with SWNT-GC
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Proceedings Volume 8944, Biophotonics and Immune Responses IX; 89440J (2014) https://doi.org/10.1117/12.2042372
Event: SPIE BiOS, 2014, San Francisco, California, United States
Abstract
In our previous work, we constructed a multifunction nano system SWNT-GC, which can synergize photothermal and immunological effects. To further improve the application of this system, we study the cytotoxicity of SWNT-GC and investigate the effects on malignant tumor therapy. Here, we selected the optimal concentration of GC and SWNTs for the stable SWNT-GC construction. No cytotoxicity was observed under the dose used in the experiments. Using mouse melanoma tumor model, Laser+SWNT-GC treatment resulted in a significant mice survival rate, there were no long-term survivors under other treatment. It is providing a promising treatment modality for the malignancy.
© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Feifan Zhou, Sheng Song, and Wei R. Chen "Special antitumor immune effects of laser immunotherapy with SWNT-GC", Proc. SPIE 8944, Biophotonics and Immune Responses IX, 89440J (27 February 2014); https://doi.org/10.1117/12.2042372
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