Construction of a digital and physical mouse model aimed at the study of electrical shock

Thu T. A. Nguyen; Jeffrey W. Shupp; Lauren T. Moffatt; Jessica C. Ramella-Roman

doi:10.1117/12.2039661

3 March 2014 Construction of a digital and physical mouse model aimed at the study of electrical shock

Thu T. A. Nguyen, Jeffrey W. Shupp, Lauren T. Moffatt, Jessica C. Ramella-Roman

Proceedings Volume 8945, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI; 894508 (2014) https://doi.org/10.1117/12.2039661
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Optical methods have been used to investigate electrical injury on animal models such as live mice, rats, and rabbits. Here we introduce a completely digital phantom of a mouse, with the aim of investigating electrical injury through spectroscopic imaging techniques. The basis of our phantom is a three-dimensional digital mouse reconstructed from co-registered computed tomographic images and cryosection by a different group. Image processing algorithms were applied to make the model suitable to Finite Element Analysis of thermal and electrical transport. Our digital model is capable of simulating temperature, voltage, current changes along the animal body during and after electrical shocks.

Citation Download Citation

Thu T. A. Nguyen, Jeffrey W. Shupp, Lauren T. Moffatt, and Jessica C. Ramella-Roman "Construction of a digital and physical mouse model aimed at the study of electrical shock", Proc. SPIE 8945, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI, 894508 (3 March 2014); https://doi.org/10.1117/12.2039661

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