4 March 2014 Multispectral imaging for diagnosis and treatment
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Abstract
A new approach for generating high-speed multispectral images has been previously reported by our team. The central concept is that spectra can be acquired for each pixel in a confocal spatial laser scan by using a fast spectrometer based on optical fiber delay lines. This method merges fast spectroscopy with standard spatial scanning to create image datacubes in real time. The datacubes can be analyzed to define regions of interest (ROIs) containing diseased tissue. Firmware and software have been developed for selectively scanning these ROIs with increased optical power. This enables real time image-guided laser treatment with a spatial resolution of a few microns.
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Gary E. Carver, Sarah A. Locknar, William A. Morrison, Daniel L. Farkas, "Multispectral imaging for diagnosis and treatment", Proc. SPIE 8947, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XII, 89470L (4 March 2014); doi: 10.1117/12.2039980; https://doi.org/10.1117/12.2039980
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