28 February 2014 Hyperspectral imaging via spectral interferometric polarised coherent anti-Stokes Raman scattering
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We have developed a new method for quantitative broadband CARS spectral imaging, which uses passive polarisation optics combined with spectrally-resolved balanced homodyne detection to remove the non-resonant background (NRB) in a single exposure. Independent measurement of the Stokes spectrum is not required for NRB removal, and the resulting spectra are amplified by the non-resonant response, vary linearly with concentration, and can be directly related to polarized spontaneous Raman spectra. The technique has relaxed requirements on spectral phase and instrument stability, is suitable for any laser system capable of generating CARS, and has been successfully applied to rapid hyperspectral Raman imaging.
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Brad Littleton, Brad Littleton, Thomas Kavanagh, Thomas Kavanagh, Frederic Festy, Frederic Festy, David Richards, David Richards, "Hyperspectral imaging via spectral interferometric polarised coherent anti-Stokes Raman scattering", Proc. SPIE 8948, Multiphoton Microscopy in the Biomedical Sciences XIV, 89482T (28 February 2014); doi: 10.1117/12.2040940; https://doi.org/10.1117/12.2040940

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