20 February 2014 Enhanced coherent anti-Stokes Raman scattering imaging using silica mircospheres
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Abstract
A technique was developed to achieve enhanced coherent anti-Stokes Raman scattering (CARS) imaging using selfassembled silica microspheres. In this study, a layer of optically transparent silica microspheres was self-assembled onto polymer grating samples to enhance the CARS signals. The highest enhancement of 12.5 was achieved using 6.1-μmdiameter microspheres for C-H molecule vibration. Finite-difference time-domain (FDTD) algorithm under the perfectly matched layer boundary condition was used to simulate the enhancement using silica microspheres of different diameters.
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X. Huang, X. Huang, X. N. He, X. N. He, W. Xiong, W. Xiong, Y. Gao, Y. Gao, L. J. Jiang, L. J. Jiang, L. Liu, L. Liu, Y. S. Zhou, Y. S. Zhou, J. F. Silvain, J. F. Silvain, L. Jiang, L. Jiang, Y. F. Lu, Y. F. Lu, } "Enhanced coherent anti-Stokes Raman scattering imaging using silica mircospheres", Proc. SPIE 8954, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI, 895402 (20 February 2014); doi: 10.1117/12.2041783; https://doi.org/10.1117/12.2041783
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