24 March 2014 Iron oxide nanoparticles in different modifications for antimicrobial phototherapy
Author Affiliations +
The main goal of this study was to investigate the sensitivity of microorganisms to combined action of blue light and iron oxide nanoparticles. Two strains of Staphylococcus aureus – methicillin-sensitive and meticillin-resistant were used. As a blue light source LED with spectral maximum at 405 nm was taken. The light exposure was ranged from 5 to 30 min. The Fe2O3 (diameter ∼27 nm), Fe3O4 nanoparticles (diameter ∼19 nm), and composite Fe2O3/TiO2 nanoparticles (diameter ∼100 nm) were synthesized. It was shown that irradiation by blue light caused from 20% to 88% decrease in the number of microorganisms treated with nanoparticles. Morphological changes in bacterial cells after phototreatment were analyzed using scanning electron microscope.
© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Elena S. Tuchina, Elena S. Tuchina, Kristina V. Kozina, Kristina V. Kozina, Nikita A. Shelest, Nikita A. Shelest, Vyacheslav I. Kochubey, Vyacheslav I. Kochubey, Valery V. Tuchin, Valery V. Tuchin, "Iron oxide nanoparticles in different modifications for antimicrobial phototherapy", Proc. SPIE 8955, Colloidal Nanoparticles for Biomedical Applications IX, 89551P (24 March 2014); doi: 10.1117/12.2038421; https://doi.org/10.1117/12.2038421

Back to Top