Evaluation of a multispectral diffuse optical spectroscopy device for assessment of cardiometabolic risk related alterations of body composition

Z. Marcinkevics; K. Volceka; L. Ozolina-Moll; J. Zaharans

doi:10.1117/12.2044685

18 November 2013 Evaluation of a multispectral diffuse optical spectroscopy device for assessment of cardiometabolic risk related alterations of body composition

Z. Marcinkevics, K. Volceka, L. Ozolina-Moll, J. Zaharans

Author Affiliations +

Proceedings Volume 9032, Biophotonics—Riga 2013; 903208 (2013) https://doi.org/10.1117/12.2044685
Event: 1st International Conference "Biophotonics Riga 2013", 2013, Riga, Latvia

Abstract

Cardiometabolic diseases encompass a combination of conditions which lead to an increase in the risk of cardiovascular disease and diabetes. With the increasing percentage of the population becoming overweight, it is important to diagnose when the excess adipose tissue becomes malign. The development of a safe, mobile, non-invasive method that would be easy to perform, and low-cost, but also would offer an accurate assessment of subcutaneous adipose tissue (SAT) both in lean and in obese persons is required. A prototype device using an optical method for measurement of the SAT in vivo has been developed, it contains multiple LEDs with four wavelengths (660nm, 780nm, 870nm, 940nm) distributed at various distances from the photodetector which allow different light penetration depths into the subcutaneous tissue. Five young healthy female students participated in the study; the measurements were performed on three body sites: calf, upper and lower abdomen. The backscattered light acquired with the prototype was compared to SAT measured with high resolution ultrasound imaging. The coefficient of variation indicated high reliability of the measurements. Statistically significant (from r=0.81 to r=0.95; p<0.05) correlation between intensity of backscattered light and SAT thicknesses for all four wavelength was observed, especially at source-detector distance 25mm. The novel device prototype has a potential to be a good alternative for conventional SAT measurement and assessment of cardiometabolic risk. Amultispectral approach can potentially increase precision and spatial resolution of SAT determination.

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Z. Marcinkevics, K. Volceka, L. Ozolina-Moll, and J. Zaharans "Evaluation of a multispectral diffuse optical spectroscopy device for assessment of cardiometabolic risk related alterations of body composition", Proc. SPIE 9032, Biophotonics—Riga 2013, 903208 (18 November 2013); https://doi.org/10.1117/12.2044685

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KEYWORDS

Light emitting diodes

Tissue optics

Sensors

Tissues

Prototyping

Abdomen

Light

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