19 March 2014 Direct spectral recovery using X-ray fluorescence measurements for material decomposition applications using photon counting spectral X-ray detectors
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Abstract
We present investigations into direct, calibration-free recovery of distorted spectral x-ray measurements with the Medipix 2 detector. Spectral x-ray measurements using pixelated photon counting spectral x-ray detectors are subject to significant spectral distortion. For detectors with small pixel size, charge sharing between adjacent electrodes often dominates this distortion. In material decomposition applications, a popular spectral recovery technique employs a calibration phantom with known spectral properties. This works due to the similarity of the attenuation properties of the phantom and the material to be studied. However, this approach may be too simplistic for clinical imaging applications as it assumes the homogeneity (and knowledge) of exactly the properties whose variation accounts entirely for the diagnostic content of the spectral data obtained by the photon counting detector. It may also be difficult to find the right calibration phantom for varying patient size and tissue densities on a case-by-case basis. Thus, it is desirable to develop direct correction strategies, based on the objectively measurable response of the detector. We model analytically the distortion of a spectral signal in a PCSXD by applying Gaussian broadening and a charge-sharing model. The model parameters are fitted to the measured fluorescence of several metals. While we are investigating the methodology using Medipix detectors, it should be applicable to other PCXDs as well.
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Tom Campbell-Ricketts, Mini Das, "Direct spectral recovery using X-ray fluorescence measurements for material decomposition applications using photon counting spectral X-ray detectors", Proc. SPIE 9033, Medical Imaging 2014: Physics of Medical Imaging, 90331D (19 March 2014); doi: 10.1117/12.2043992; https://doi.org/10.1117/12.2043992
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