19 March 2014 X-ray pulsing methods for reduced-dose computed tomography in PET/CT attenuation correction
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The image quality needed for CT-based attenuation correction (CTAC) is significantly lower than what is used currently for diagnostic CT imaging. Consequently, the X-ray dose required for sufficient image quality with CTAC is relatively small, potentially smaller than the lowest X-ray dose clinical CT scanners can provide. Operating modes have been proposed in which the X-rays are periodically turned on and off during the scan in order to reduce X-ray dose. This study reviews the different methods by which X-rays can be modulated in a CT scanner, and assesses their adequacy for lowdose acquisitions as required for CTAC. Calculations and experimental data are provided to exemplify selected X-ray pulsing scenarios. Our analysis shows that low-dose pulsing is possible but challenging with clinically available CT tubes. Alternative X-ray tube designs would lift this restriction.
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Uwe Wiedmann, V. Bogdan Neculaes, Dan Harrison, Evren Asma, Paul E. Kinahan, Bruno De Man, "X-ray pulsing methods for reduced-dose computed tomography in PET/CT attenuation correction", Proc. SPIE 9033, Medical Imaging 2014: Physics of Medical Imaging, 90332Z (19 March 2014); doi: 10.1117/12.2043021; https://doi.org/10.1117/12.2043021

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