19 March 2014 Design of a compact high-energy setup for x-ray phase-contrast imaging
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The main shortcoming of conventional biomedical x-ray imaging is the weak soft-tissue contrast caused by the small differences in the absorption coefficients between different materials. This issue can be addressed by x-ray phasesensitive imaging approaches, e.g. x-ray Talbot-Lau grating interferometry. The advantage of the three-grating Talbot-Lau approach is that it allows to acquire x-ray phase-contrast and dark-field images with a conventional lab source. However, through the introduction of the grating interferometer some constraints are imposed on the setup geometry. In general, the grating pitch and the mean x-ray energy determine the setup dimensions. The minimal length of the setup increases linearly with energy and is proportional to p2, where p is the grating pitch. Thus, a high-energy (100 keV) compact grating-based setup for x-ray imaging can be realized only if gratings with aspect-ratio of approximately 300 and a pitch of 1-2 μm were available. However, production challenges limit the availability of such gratings. In this study we consider the use of non-binary phase-gratings as means of designing a more compact grating interferometer for phase-contrast imaging. We present simulation and experimental data for both monochromatic and polychromatic case. The results reveal that phase-gratings with triangular-shaped structures yield visibilities that can be used for imaging purposes at significantly shorter distances than binary gratings. This opens the possibility to design a high-energy compact setup for x-ray phase-contrast imaging. Furthermore, we discuss different techniques to achieve triangular-shaped phase-shifting structures.
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Markus Schüttler, Markus Schüttler, Andre Yaroshenko, Andre Yaroshenko, Martin Bech, Martin Bech, Guillaume Potdevin, Guillaume Potdevin, Andreas Malecki, Andreas Malecki, Michael Chabior, Michael Chabior, Johannes Wolf, Johannes Wolf, Arne Tapfer, Arne Tapfer, Jan Meiser, Jan Meiser, Danays Kunka, Danays Kunka, Maximilian Amberger, Maximilian Amberger, Jürgen Mohr, Jürgen Mohr, Franz Pfeiffer, Franz Pfeiffer, "Design of a compact high-energy setup for x-ray phase-contrast imaging", Proc. SPIE 9033, Medical Imaging 2014: Physics of Medical Imaging, 90334Y (19 March 2014); doi: 10.1117/12.2042892; https://doi.org/10.1117/12.2042892


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